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How is Cutaneous Lupus Treated?
Published: Jan 27, 2024
Treating cutaneous lupus involves various strategies to manage symptoms and prevent skin damage. Let's explore the options available.
First-Line Treatments
Photoprotection is crucial, as UV light can worsen the condition. Topical corticosteroids and calcineurin inhibitors are commonly used to reduce inflammation. Antimalarial drugs like hydroxychloroquine are often prescribed, showing benefits in skin symptom management.
Advanced Options
For those who don't respond to first-line treatments, immunomodulatory agents like methotrexate and mycophenolate mofetil may be used. Thalidomide and lenalidomide are other options, though they require careful monitoring due to possible side effects.
Innovative Therapies
New treatments like JAK inhibitors and biologics such as rituximab are being explored for their effectiveness in cutaneous lupus. These therapies offer hope for patients with treatment-resistant cases.
Frequently Asked Questions
Photoprotection and topical treatments are the first steps.
Yes, immunomodulatory agents and biologics are available.
Yes, they are often used to manage skin symptoms.
JAK inhibitors and biologics like rituximab are promising.
The Bottom Line
A variety of treatments exist for cutaneous lupus, from traditional to innovative therapies.
References
- Chasset F, Bouaziz JD, Costedoat-Chalumeau N, et al. Efficacy and comparison of antimalarials in cutaneous lupus erythematosus subtypes: a systematic review and meta-analysis. Br J Dermatol 2017; 177:188.
- Riley K, Schwager Z, Stern M, et al. Assessment of Antimalarial Therapy in Patients Who Are Hypersensitive to Hydroxychloroquine. JAMA Dermatol 2019; 155:491.
This article has been reviewed for accuracy by one of the licensed medical doctors working for Doctronic. Always discuss health information with your healthcare provider.
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