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How is Acute Myeloid Leukemia Diagnosed?
Published: May 23, 2024
Diagnosing Acute Myeloid Leukemia (AML) involves a series of tests and evaluations. Here's what you need to know.
Blood Tests
The first step in diagnosing AML is usually a complete blood count (CBC) to check for abnormal levels of white blood cells, red blood cells, and platelets. If the CBC indicates possible leukemia, a blood smear is examined under a microscope to look for leukemia cells.
Bone Marrow Examination
A bone marrow biopsy and aspiration are typically performed to confirm AML. During this procedure, a small amount of bone marrow is removed and examined for leukemia cells. This test provides detailed information about the types and numbers of cells in the marrow.
Genetic Testing
Genetic tests are conducted to identify specific mutations or chromosomal changes in leukemia cells. These tests help classify the type of AML, guide treatment decisions, and predict patient outcomes.
Frequently Asked Questions
A CBC is a blood test that measures various blood cell levels.
A biopsy confirms the presence of leukemia cells in the marrow.
They identify mutations that guide treatment and prognosis.
The Diagnosis Journey
Accurate diagnosis is crucial for effective treatment planning and management.
References
- Arber DA, Orazi A, Hasserjian RP, et al. International Consensus Classification of Myeloid Neoplasms and Acute Leukemias: integrating morphologic, clinical, and genomic data. Blood 2022; 140:1200.
- Duncavage EJ, Bagg A, Hasserjian RP, et al. Genomic profiling for clinical decision making in myeloid neoplasms and acute leukemia. Blood 2022; 140:2228.
This article has been reviewed for accuracy by one of the licensed medical doctors working for Doctronic. Always discuss health information with your healthcare provider.
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