How is a Refractory Peptic Ulcer Diagnosed?
Published: Mar 09, 2024
Diagnosing refractory peptic ulcers can be tricky, but understanding the process is key to effective treatment. Learn about the tests used to confirm and understand these persistent ulcers.
Contents
The Role of Endoscopy
Endoscopy is a crucial tool for diagnosing refractory peptic ulcers. This procedure involves using a small camera to look inside the stomach and identify any ulcers. It's also used to take tissue samples, which help rule out cancer or other conditions.
Understanding Biopsies
During an endoscopy, biopsies are often taken from the ulcer and surrounding tissue. These samples are tested for Helicobacter pylori, a common cause of ulcers. Biopsies can also detect other diseases like Crohn's disease that might be contributing to ulcer persistence.

Additional Testing
If ulcers persist despite treatment, additional tests may be needed. Tests measuring stomach acid levels or looking for specific hormonal imbalances can provide further insights. This detailed testing helps pinpoint the exact cause and guide the treatment plan.
Frequently Asked Questions
It's a procedure using a camera to view the stomach lining.
To test for H. pylori and rule out other diseases.
Sometimes, to find the exact cause of persistent ulcers.
The Bottom Line
Accurate diagnosis of refractory ulcers ensures targeted and effective treatment.
References
- Yuan Y, Padol IT, Hunt RH. Nat Clin Pract Gastroenterol Hepatol 2006; 3:80.
- Goodman AJ, Kerrigan DD, Johnson AG. Br J Surg 1987; 74:897.
This article has been reviewed for accuracy by one of the licensed medical doctors working for Doctronic. Always discuss health information with your healthcare provider.
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