How Genetic Testing Can Change Cancer Treatments
Published: Sep 29, 2023
Genetic testing can influence the treatment options for individuals at risk of hereditary cancers, leading to more personalized and effective care.
Contents
The Power of Genetic Tests
Genetic tests can identify specific changes in genes that increase cancer risk. This information can guide doctors in deciding the best treatment plans. For instance, certain drugs are more effective in patients with specific genetic mutations.
Choosing the Right Treatment
For those with a BRCA1 or BRCA2 variant, treatments like PARP inhibitors can be particularly effective. These drugs target cancer cells' ability to repair DNA, which is often compromised in these patients. This approach can extend disease-free survival in some cancer cases.

When to Consider Genetic Testing
Patients with a family history of cancer or personal history of certain cancers are prime candidates for genetic testing. Performing these tests can shed light on available treatment paths and preventive measures. It's crucial to work with a healthcare provider to determine the best course of action.
Frequently Asked Questions
It helps tailor treatments based on genetic mutations.
Drugs effective for patients with BRCA mutations.
Those with a family or personal history of certain cancers.
Key Takeaways
Genetic testing is a valuable tool in designing personalized cancer treatment plans.
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References
Tutt ANJ, Garber JE, Kaufman B, et al. N Engl J Med 2021; 384:2394.
National Comprehensive Cancer Network. Genetics Guidelines.
Always discuss health information with your healthcare provider.