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Contents
  • Calcium and PTH Levels
  • 24-Hour Urinary Calcium Excretion
  • Role of Vitamin D Testing

How Do You Test for Primary Hyperparathyroidism?

How Do You Test for Primary Hyperparathyroidism?

The Big Picture

Testing for primary hyperparathyroidism (PHPT) involves several steps to confirm the diagnosis. Learn which tests are crucial and what they reveal about your health.
Contents
  • Calcium and PTH Levels
  • 24-Hour Urinary Calcium Excretion
  • Role of Vitamin D Testing

Calcium and PTH Levels

The initial test for PHPT is measuring serum calcium levels. If levels are high, a parathyroid hormone (PTH) test follows. Elevated or normal PTH in the presence of high calcium can indicate PHPT. These tests are critical first steps in diagnosing the condition.

24-Hour Urinary Calcium Excretion

A 24-hour urine test measures calcium excretion, helping distinguish PHPT from other conditions like familial hypocalciuric hypercalcemia (FHH). High urinary calcium suggests PHPT, while low levels may indicate FHH. This test is vital for accurate diagnosis and treatment planning.
Primary hyperparathyroidism is a condition characterized by the overproduction of parathyroid hormone (PTH) leading to elevated calcium levels in the blood.

Role of Vitamin D Testing

Vitamin D levels are often tested because a deficiency can mask PHPT symptoms. Low vitamin D can lead to incorrect diagnoses, so measuring it ensures a comprehensive view of calcium-related health. Correcting a deficiency can also reveal hidden PHPT.

FAQs

What is the first test for PHPT?

The first test is measuring serum calcium levels.

Why test urinary calcium?

It helps distinguish PHPT from similar conditions.

Does vitamin D affect PHPT tests?

Yes, low vitamin D can mask PHPT symptoms.

What does high PTH indicate?

High PTH alongside high calcium suggests PHPT.

Wrapping Up

Could these tests uncover a hidden condition affecting you?
Discuss your test results with Doctronic to understand your health more clearly.
Additional References
  1. Silverberg SJ, Clarke BL, Peacock M, et al. Current issues in the presentation of asymptomatic primary hyperparathyroidism: proceedings of the Fourth International Workshop. J Clin Endocrinol Metab 2014; 99:3580.
  2. Crowley RK, Gittoes NJ. Elevated PTH with normal serum calcium level: a structured approach. Clin Endocrinol (Oxf) 2016; 84:809.
This article has been reviewed for accuracy by one of the licensed medical doctors working for Doctronic.