How Do Doctors Diagnose Dementia with Lewy Bodies?
Published: Dec 16, 2023
Diagnosing dementia with Lewy bodies can be tricky due to its similarities with other dementias. Learn about the tests and criteria used to identify this condition.
Contents
Core Clinical Features
To diagnose DLB, doctors look for key symptoms like cognitive fluctuations, visual hallucinations, and REM sleep behavior disorder. These symptoms often appear early and persist, making them helpful in distinguishing DLB from other types of dementia.
Imaging Tests
Imaging tests such as MRI and SPECT scans play a crucial role in diagnosing DLB. These tests can reveal specific brain changes and help differentiate DLB from Alzheimer's and Parkinson's diseases.

Biomarkers and Other Tests
While not yet widely available, certain biomarkers can indicate DLB. These include dopamine transporter imaging and myocardial scintigraphy, which show specific patterns in brain and heart activity.
Frequently Asked Questions
MRI, SPECT scans, and cognitive assessments are commonly used.
Imaging helps identify brain changes specific to DLB.
They are biological signs that suggest the presence of DLB.
Not yet, but they provide supportive evidence.
The Bottom Line
Accurate diagnosis of DLB relies on a combination of clinical features, imaging, and potential biomarkers.
References
- McKeith IG, Boeve BF, Dickson DW, et al. Diagnosis and management of dementia with Lewy bodies: Fourth consensus report of the DLB Consortium. Neurology 2017; 89:88.
- O'Brien JT, McKeith IG, Walker Z, et al. Diagnostic accuracy of 123I-FP-CIT SPECT in possible dementia with Lewy bodies. Br J Psychiatry 2009; 194:34.
This article has been reviewed for accuracy by one of the licensed medical doctors working for Doctronic. Always discuss health information with your healthcare provider.
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