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Heparin in Pregnancy: A Safe Blood Thinner for Two
Published: Apr 02, 2024
Heparin is a common blood thinner used during pregnancy to prevent dangerous clots. It's considered safe for both mother and baby, but requires careful management.
Types of Heparin Used in Pregnancy
There are two main types of heparin used during pregnancy: unfractionated heparin and low molecular weight heparin (LMWH). LMWH is generally preferred because it's easier to use and has a more predictable effect. Both types are given as injections under the skin.
How Heparin Works
Heparin works by interfering with the blood's clotting process. It doesn't break up existing clots, but it prevents new ones from forming. Unlike some other blood thinners, heparin doesn't cross the placenta, making it safe for the developing baby.
Dosing and Monitoring
The dose of heparin needed often increases as pregnancy progresses. Your doctor will determine the right dose based on your weight and risk factors. Regular blood tests may be needed to ensure the heparin is working correctly without causing excessive bleeding risk.
Managing Heparin Around Delivery
As you near your due date, your doctor will create a plan for managing your heparin use. This usually involves stopping the medication before labor begins to reduce the risk of excessive bleeding during delivery. After delivery, heparin or another blood thinner is often restarted to protect against postpartum blood clots.
Frequently Asked Questions
No, heparin doesn't cross the placenta and isn't associated with birth defects.
Typically once or twice daily, depending on the type and your doctor's instructions.
Yes, heparin is considered safe for breastfeeding mothers.
Common side effects include bruising at injection sites and rarely, excessive bleeding.
Usually at least 6 weeks, but it depends on your individual risk factors.
The Bottom Line
Heparin provides crucial protection against blood clots during pregnancy and postpartum, with minimal risk to the baby.
References
- Bates SM, et al. American Society of Hematology 2018 guidelines for management of venous thromboembolism: venous thromboembolism in the context of pregnancy. Blood Adv 2018; 2:3317.
- Greer IA, Nelson-Piercy C. Low-molecular-weight heparins for thromboprophylaxis and treatment of venous thromboembolism in pregnancy: a systematic review of safety and efficacy. Blood 2005; 106:401.
This article has been reviewed for accuracy by one of the licensed medical doctors working for Doctronic. Always discuss health information with your healthcare provider.
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