Exploring Therapies for cSCC: What Are Your Options?
Published: Jan 19, 2024
Cutaneous squamous cell carcinoma (cSCC) treatment involves various therapies. Learn about your options to make informed decisions.
Contents
Surgical Treatments
Surgery is a common treatment for cSCC and involves removing the cancerous tissue. Options include excision, Mohs surgery, or curettage and electrodessication. The choice depends on the size and location of the cancer.
Topical and Systemic Therapies
For less invasive cases, topical treatments like fluorouracil or imiquimod may be used. Systemic therapies, such as oral retinoids, are considered for high-risk patients. These treatments aim to prevent cancer spread and recurrence.

Radiation Therapy
Radiation therapy is a non-surgical option for treating cSCC, especially in cases where surgery isn't possible. It uses high-energy rays to kill cancer cells and shrink tumors. This therapy is often used for tumors in challenging locations.
Frequently Asked Questions
Surgery is the most common treatment option.
Yes, they can be used for less invasive cases.
Radiation is used when surgery isn't feasible.
The Bottom Line
Exploring all therapy options helps craft the right treatment plan for youβwhat will you choose?
References
- Work Group, Invited Reviewers, Kim JYS, et al. Guidelines of care for the management of cutaneous squamous cell carcinoma. J Am Acad Dermatol 2018; 78:560.
- Weinstock MA, Bingham SF, Digiovanna JJ, et al. Tretinoin and the prevention of keratinocyte carcinoma. J Invest Dermatol 2012; 132:1583.
This article has been reviewed for accuracy by one of the licensed medical doctors working for Doctronic. Always discuss health information with your healthcare provider.
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