Effective Treatments for Perioral Dermatitis
Published: Apr 23, 2024
Learn about the best treatment options available to help clear up perioral dermatitis and restore your skin's health.
Contents
Topical Treatments
For mild perioral dermatitis, topical treatments are often recommended. Popular options include topical calcineurin inhibitors like pimecrolimus and tacrolimus, which help reduce inflammation. Antibiotic creams such as metronidazole and erythromycin can also be effective, offering a non-systemic approach to manage the condition.
Oral Medications
In more severe cases, oral medications might be necessary. Tetracyclines, including doxycycline and minocycline, are commonly prescribed to reduce inflammation and bacterial presence. For children or those unable to take tetracyclines, alternatives like erythromycin may be considered.

Alternative Therapies
Some patients find relief with alternative treatments like ivermectin, azelaic acid, or sulfur-based products. Though not as well-studied, these options can be considered for those not responding to conventional therapies. It's crucial to consult with a healthcare provider before trying these alternatives.
Frequently Asked Questions
Pimecrolimus, tacrolimus, metronidazole, and erythromycin.
Tetracyclines like doxycycline and minocycline.
Yes, options include ivermectin and azelaic acid.
Key Takeaways
With the right treatment, perioral dermatitis can be effectively managed.
References
- Schwarz T, Kreiselmaier I, Bieber T, et al. A randomized study of 1% pimecrolimus cream in perioral dermatitis. J Am Acad Dermatol 2008; 59:34.
- Weber K, Thurmayr R, Meisinger A. Topical erythromycin and oral tetracycline for perioral dermatitis: a trial. J Dermatol Treat 1993; 4:57.
This article has been reviewed for accuracy by one of the licensed medical doctors working for Doctronic. Always discuss health information with your healthcare provider.
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