Do Your Genes Hold the Key to Narcolepsy?
Published: Oct 02, 2023

Medically reviewed by Angel Kerney | MD, F.A.C.O.G Obstetrics & Gynecology on October 2nd, 2023.
Your genes may significantly impact your risk of developing narcolepsy. Discover how genetic factors and environmental triggers can influence this condition.
Contents
Genetic Risk Factors
The DQB1*0602 haplotype is a significant genetic risk factor for Type 1 narcolepsy, present in most affected individuals. Other human leukocyte antigen (HLA) haplotypes can also impact risk. Understanding your genetic predisposition can provide insight into your narcolepsy risk.
Environmental Triggers
While genetics play a role, environmental factors like infections can trigger narcolepsy. Streptococcus and influenza are known triggers. These factors are crucial in understanding and managing narcolepsy risk.

Narcolepsy in Families
Narcolepsy sometimes runs in families, though this is rare. Family members may experience isolated symptoms or even narcolepsy without genetic markers. This suggests a complex interplay of genetic and environmental factors.
Frequently Asked Questions
Yes, certain genetic markers like DQB1*0602 increase risk.
Infections like streptococcus and influenza can trigger it.
Yes, though it's rare and complex.
Key Takeaways
Understanding genetic and environmental factors is key to managing narcolepsy risk.
Explore your narcolepsy risk factors with Doctronic today!Related Articles
References
Mignot E, Lammers GJ, Ripley B, et al. The role of cerebrospinal fluid hypocretin measurement in the diagnosis of narcolepsy and other hypersomnias. Arch Neurol 2002; 59:1553.
Bourgin P, Zeitzer JM, Mignot E. CSF hypocretin-1 assessment in sleep and neurological disorders. Lancet Neurol 2008; 7:649.
This article has been reviewed for accuracy by one of the licensed medical doctors working for Doctronic. Always discuss health information with your healthcare provider.