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Disease-Modifying Therapies for MS: What Are Your Options?
Published: Mar 18, 2024
Disease-modifying therapies (DMTs) are the cornerstone of multiple sclerosis treatment. But with so many options available, how do you know which one is right for you?
Types of DMTs
DMTs for MS fall into three main categories: injectable drugs, oral medications, and infusion therapies. Injectable drugs, like interferons and glatiramer acetate, were the first DMTs developed. Oral medications include drugs like dimethyl fumarate and fingolimod. Infusion therapies, such as natalizumab and ocrelizumab, are administered intravenously at a healthcare facility.
Choosing the Right DMT
Selecting a DMT is a personalized process that depends on various factors. These include the severity of your MS, other health conditions you may have, your lifestyle preferences, and potential side effects. Some DMTs are more effective but carry higher risks, while others may be safer but less potent. Your neurologist will work with you to find the best balance for your situation.
Monitoring Treatment Effectiveness
Once you start a DMT, regular monitoring is crucial. This typically involves clinical check-ups, MRI scans, and sometimes blood tests. Your doctor will look for signs of disease activity, such as new relapses or MRI lesions. If your current DMT isn't effectively controlling your MS, your doctor may recommend switching to a different therapy.
Frequently Asked Questions
It can take 3-6 months to see full effects.
No, DMTs are typically long-term treatments.
No, but they can significantly slow disease progression.
The Future of MS Treatment
As research continues, new and more effective DMTs are being developed, offering hope for even better MS management in the future.
References
- Rae-Grant A, et al. Practice guideline recommendations summary: Disease-modifying therapies for adults with multiple sclerosis. Neurology 2018; 90:777.
- Montalban X, et al. ECTRIMS/EAN Guideline on the pharmacological treatment of people with multiple sclerosis. Mult Scler 2018; 24:96.
- Gross RH, Corboy JR. Monitoring, Switching, and Stopping Multiple Sclerosis Disease-Modifying Therapies. Continuum (Minneap Minn) 2019; 25:715.
This article has been reviewed for accuracy by one of the licensed medical doctors working for Doctronic. Always discuss health information with your healthcare provider.
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