Cushing Syndrome: Could You Be Affected?
Published: Mar 26, 2024
Cushing syndrome is a condition with a variety of causes, leading to excessive cortisol levels. Understanding this condition can help identify and manage it effectively.
Contents
Understanding Cushing Syndrome
Cushing syndrome results from high cortisol levels in the body. It might be due to the body's overproduction of cortisol or from external sources like medications. Symptoms include weight gain, high blood pressure, and changes in the skin.
Types and Causes
The syndrome can be categorized as ACTH-dependent or ACTH-independent. ACTH-dependent includes conditions like Cushing disease, whereas ACTH-independent often involves adrenal tumors. Iatrogenic Cushing syndrome is due to glucocorticoid medications.

Diagnosis and Differentiation
Diagnosis requires understanding the source of cortisol excess. Tests differentiate between ACTH-dependent and independent types, and exclude pseudo-Cushing syndrome, which mimics the condition.
Frequently Asked Questions
Weight gain, high blood pressure, and skin changes are common symptoms.
Diagnosis involves tests to determine the source of cortisol excess.
It's a condition that mimics Cushing syndrome but isn't true hypercortisolism.
Yes, glucocorticoid medications can lead to iatrogenic Cushing syndrome.
Wrapping Up
Understanding Cushing syndrome's types and symptoms is crucial for effective management.
References
- Kling MA, Roy A, Doran AR, et al. J Clin Endocrinol Metab 1991; 72:260.
- Chabre O. Presse Med 2014; 43:376.
This article has been reviewed for accuracy by one of the licensed medical doctors working for Doctronic. Always discuss health information with your healthcare provider.
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