Could Your Medication Be Causing Angioedema?
Published: Feb 19, 2024
Angioedema can be a scary side effect of certain medications. Let's dive into what causes it and how to recognize the symptoms.
Contents
Understanding Angioedema
Angioedema is a swelling of the deeper layers of the skin, often affecting the face, lips, and sometimes the throat, which can be life-threatening if it blocks the airway. It is often accompanied by hives and is usually caused by drug allergies. Common triggers include antibiotics, NSAIDs, and ACE inhibitors.
Timing and Triggers
Angioedema can occur at any time during drug treatment, although it's more common in the first few weeks. ACE inhibitors are notorious for causing this reaction, sometimes months after starting the medication. Non-IgE-mediated mechanisms are often involved, leading to swelling without any other allergic symptoms.

Quick Action is Key
If angioedema affects the airway, it's a medical emergency. Treatment often involves stopping the offending drug and administering antihistamines or corticosteroids. In severe cases, epinephrine may be required to reduce swelling quickly and restore normal breathing.
Frequently Asked Questions
It's a swelling of deeper skin layers, often on the face or throat.
Antibiotics, NSAIDs, and ACE inhibitors are common triggers.
It can occur anytime, but usually within the first few weeks of drug use.
Yes, if it affects the airway, immediate treatment is crucial.
Stay Alert
Recognizing angioedema symptoms early can save lives.
References
- Kanani A, et al. Urticaria and angioedema. Allergy Asthma Clin Immunol 2018.
- Stone C Jr, Brown NJ. Drug-associated Angioedema. Immunol Allergy Clin North Am 2017.
This article has been reviewed for accuracy by one of the licensed medical doctors working for Doctronic. Always discuss health information with your healthcare provider.
AI Doctor Visit Required
Appointments available 24/7
15-min consultation. No hidden costs.
AI Doctor Visit Required
For safety reasons we have been forced to end this consultation.
If you believe this is a medical emergency please call 911 or your local emergency services immediately.
If you are experiencing emotional distress, please call the the Suicide & Crisis Lifeline at 988 or your local crisis services immediately.
Contact us
You can also email us at help@doctronic.ai
We aim to reply within 5-7 days
How likely are you to recommend Doctronic to friends or family?