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Could You Have Paget Disease of the Breast and Not Know It?
Published: Apr 16, 2024
Paget disease of the breast is a rare condition that could be mistaken for less serious skin issues. Knowing its signs can make all the difference.
What is Paget Disease of the Breast?
Paget disease of the breast (PDB) is a rare type of breast cancer that starts on the nipple and can spread to the areola. It appears as a scaly, itchy, or ulcerated lesion on the skin. Though it looks like a skin condition, it often signals underlying breast cancer, affecting 85 to 88 percent of cases.
Who is at Risk?
PDB is much less common than other forms of breast cancer, making up only 1 to 3 percent of cases. It mostly affects women between the ages of 50 and 60. While men can develop PDB, it's extremely rare. Thanks to better screening, its incidence is decreasing.
Symptoms to Watch For
Common symptoms include a persistent rash, bleeding, or discharge from the nipple. It may also cause burning or itching sensations. If you notice these symptoms, especially if they last over a month, it's crucial to see a doctor.
Diagnosis and Treatment
Diagnosis typically involves a skin biopsy of the nipple. Treatment often requires surgery, either mastectomy or breast-conserving surgery, depending on the extent of the underlying cancer. Radiotherapy is usually recommended after surgery.
Frequently Asked Questions
It's a rare form of breast cancer starting at the nipple.
Women aged 50 to 60 are most at risk.
Symptoms include nipple rash, bleeding, and itching.
A skin biopsy of the nipple is used for diagnosis.
Surgery and radiotherapy are common treatments.
Key Takeaways
Recognizing the symptoms of Paget disease early can lead to prompt treatment and better outcomes.
References
- Paget J. On disease of the mammary areola preceding cancer of the mammary gland. Bartholomew's Hosp Rep 1874; 10:87.
- Thin G. On the connection between disease of the nipple and areola and tumors of the breast. Trans Pathol Soc Lond 1881; 32:218.
- Sisti A, Huayllani MT, Restrepo DJ, et al. Paget disease of the breast: A national retrospective analysis of the US population. Breast Dis 2020; 39:119.
This article has been reviewed for accuracy by one of the licensed medical doctors working for Doctronic. Always discuss health information with your healthcare provider.
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