Can These Treatments Slow Cognitive Decline in Parkinson's?

Published: Dec 29, 2023

While there's no cure for cognitive decline in Parkinson's, certain treatments may offer some relief and improve quality of life.

Cholinesterase Inhibitors

Cholinesterase inhibitors are suggested for patients with Parkinson's disease dementia (PDD). These medications can modestly improve cognition, though they may come with side effects like nausea and worsened tremors.

Memantine's Role

Memantine, another medication, has shown mixed results in PD patients. While it may improve some cognitive functions, it can also cause hallucinations in some cases, necessitating careful monitoring.

Cognitive decline associated with Parkinson's disease, exploring treatments such as cholinesterase inhibitors and memantine to manage symptoms.

Managing Psychosis

Antiparkinsonian medications can lead to visual hallucinations and delusions, especially in advanced stages. Adjusting these medications can alleviate symptoms, but may require the cautious use of antipsychotic drugs.

Frequently Asked Questions

Yes, they can offer modest cognitive improvement.

Memantine's effects are mixed, with some risk of hallucinations.

Yes, but it may require careful use of antipsychotics.

Possible side effects include nausea and worsened tremors.

Key Takeaways

While no treatment stops cognitive decline in PD, some therapies can improve symptoms and quality of life.

Interested in learning more about PD treatments? Connect with Doctronic now!

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References

Emre M, Aarsland D, Albanese A, et al. Rivastigmine for dementia associated with Parkinson's disease. N Engl J Med 2004; 351:2509.

Aarsland D, Ballard C, Walker Z, et al. Memantine in patients with Parkinson's disease dementia or dementia with Lewy bodies: a double-blind, placebo-controlled, multicentre trial. Lancet Neurol 2009; 8:613.

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