Can Medical Therapy Cure Peyronie's Disease?
Published: Sep 08, 2024
While Peyronie's disease can be challenging, medical therapies offer hope for those seeking relief. Let's dive into the latest treatment options and their effectiveness.
Contents
Oral Medications
One common oral treatment for Peyronie's disease is pentoxifylline, which helps reduce inflammation and prevent scar tissue formation. Although not universally recommended, some studies suggest it may stabilize the condition in its early stages. It's generally well-tolerated, offering an option for patients looking to manage symptoms non-invasively.
Intralesional Injections
Intralesional injections, particularly with collagenase clostridium histolyticum, have shown promise in treating Peyronie's disease. This therapy involves injecting enzymes directly into the plaque to break down scar tissue, thus reducing curvature. Studies have reported significant improvements, though potential side effects like bruising and pain should be considered.

Penile Traction Therapy
Penile traction therapy is another non-surgical treatment that involves using a device to gently stretch the penis. When used alongside medical treatments, traction can improve curvature and penile length. While time-consuming, this method is favored for its non-invasive nature and has shown promising results in combination therapies.
Frequently Asked Questions
It's an oral medication that reduces inflammation in Peyronie's disease.
They break down scar tissue directly in the penis to reduce curvature.
Yes, especially when combined with other treatments, it can improve outcomes.
Possible side effects include bruising and temporary pain from injections.
Wrapping Up
Medical therapies offer varied solutions for those with Peyronie's disease, each with its benefits and considerations.
References
- Brant WO, Dean RC, Lue TF. Treatment of Peyronie's disease with oral pentoxifylline. Nat Clin Pract Urol 2006; 3:111.
- Gelbard M, Goldstein I, Hellstrom WJ, et al. Clinical efficacy, safety and tolerability of collagenase clostridium histolyticum for the treatment of peyronie disease. J Urol 2013; 190:199.
- Levine LA, Newell M, Taylor FL. Penile traction therapy for treatment of Peyronie's disease: a single-center pilot study. J Sex Med 2008; 5:1468.
This article has been reviewed for accuracy by one of the licensed medical doctors working for Doctronic. Always discuss health information with your healthcare provider.
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