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Can Long-Term Antibiotics Help in COPD?
Published: Feb 19, 2024
Long-term antibiotics could be a solution for frequent COPD flare-ups. Let's investigate how they work and if they're right for you.
The Case for Long-Term Antibiotics
In patients with severe COPD and frequent exacerbations, long-term antibiotics like azithromycin may reduce the number of flare-ups. These medications work by preventing infections and reducing inflammation in the airways.
Weighing the Pros and Cons
While long-term antibiotic use can prevent exacerbations, it also carries risks such as antibiotic resistance and adverse effects. Patients must weigh these risks against the benefits, especially if other treatments haven't been effective.
Who Should Consider This Therapy?
Long-term antibiotics are typically reserved for those with severe COPD and frequent flare-ups, despite optimal management with other treatments. A healthcare provider can help determine if this therapy is suitable for you.
Frequently Asked Questions
They are used to reduce the frequency of exacerbations.
Risks include antibiotic resistance and adverse effects.
Patients with severe COPD and frequent flare-ups.
Key Takeaways
Long-term antibiotics may benefit certain COPD patients, but it's essential to consider the risks.
References
- Albert RK, Connett J, Bailey WC, et al. Azithromycin for prevention of exacerbations of COPD. N Engl J Med 2011; 365:689.
- Uzun S, Djamin RS, Kluytmans JA, et al. Azithromycin maintenance treatment in patients with frequent exacerbations of chronic obstructive pulmonary disease (COLUMBUS): a randomised, double-blind, placebo-controlled trial. Lancet Respir Med 2014; 2:361.
This article has been reviewed for accuracy by one of the licensed medical doctors working for Doctronic. Always discuss health information with your healthcare provider.
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