Boosting Your Platelets: Treatments for Low Platelet Count
Published: May 31, 2024
If you've been diagnosed with a low platelet count, you're not alone. The good news is that there are several effective treatments available. Let's explore the options for boosting those tiny but mighty blood cells.
Contents
First Line Treatments
For many patients with immune thrombocytopenia (ITP), the most common cause of low platelets, corticosteroids are the first treatment choice. These medications, like prednisone, work by reducing the immune system's attack on platelets. Another early option is intravenous immunoglobulin (IVIG), which provides a quick but temporary boost to platelet counts.
Second Line Options
If first-line treatments aren't effective, there are other options. Thrombopoietin receptor agonists (TPO-RAs) like eltrombopag or romiplostim can stimulate the bone marrow to produce more platelets. Rituximab, a medication that targets certain immune cells, is another possibility. In some cases, removal of the spleen (splenectomy) may be considered, as the spleen is often responsible for destroying platelets.

Treating the Underlying Cause
Sometimes, low platelets are a symptom of another condition. In these cases, treating the root cause is key. For example, if a medication is causing the problem, stopping or changing that medication may solve it. If an infection is the culprit, treating the infection can help platelet counts recover. Your doctor will work to identify and address any underlying issues.
Emergency Treatments
In cases of severe thrombocytopenia or active bleeding, platelet transfusions may be necessary. This provides a quick but temporary increase in platelet count. It's typically reserved for emergencies or to prepare for surgery. In life-threatening situations, a combination of treatments may be used to rapidly increase platelet counts.
Frequently Asked Questions
It varies; some work within days, others may take weeks.
Yes, all treatments have potential side effects. Discuss these with your doctor.
A healthy diet supports overall health, but won't significantly increase platelets alone.
Not always. Mild cases may only need monitoring.
Some show promise, but discuss with your doctor before trying any.
A Personalized Approach
Treatment for low platelets isn't one-size-fits-all; your doctor will tailor a plan to your specific needs.
References
- Neunert C, et al. American Society of Hematology 2019 guidelines for immune thrombocytopenia. Blood Adv. 2019;3(23):3829-3866.
- Zufferey A, et al. Pathogenesis and therapeutic approaches in immune thrombocytopenia. J Clin Med. 2021;10(4):789.
- Cooper N, Ghanima W. Immune thrombocytopenia. N Engl J Med. 2019;381(10):945-955.
This article has been reviewed for accuracy by one of the licensed medical doctors working for Doctronic. Always discuss health information with your healthcare provider.
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