Doctors typically use two main types of antibiotics to treat Legionnaires' disease: fluoroquinolones (like levofloxacin) and macrolides (like azithromycin). These antibiotics are preferred because they can effectively kill the bacteria, reach high concentrations inside cells, and penetrate lung tissue well. Think of them as specially trained soldiers that can infiltrate the bacteria's hideouts and take them down.

Most patients are treated for at least 5 days, but treatment continues until the patient has been fever-free for 48 hours and shows clinical improvement. It's like making sure the fire is completely out before stopping the water. Patients with severe pneumonia or other health issues may need 7-10 days of treatment. Immunocompromised patients often require at least 14 days of antibiotics.

Doctors closely monitor patients' response to treatment. Most people start feeling better within 2-5 days of starting antibiotics. However, chest X-rays may take up to two months to show full improvement. It's like cleaning up after a storm - the immediate mess gets cleared quickly, but some repairs take longer.

Prompt, appropriate antibiotic treatment is key to successfully treating Legionnaires' disease and preventing complications.