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Are You at Risk? Identifying Cancer Triggers in IBD Patients
Published: May 25, 2024
Understanding what increases your cancer risk can help you take control of your health, especially if you have IBD.
Inflammation: The Silent Culprit
Chronic inflammation is a significant risk factor for colorectal cancer in IBD patients. The longer and more severe the inflammation, the greater the risk. Identifying and managing inflammation early can help mitigate this risk.
The Role of Pseudopolyps
Pseudopolyps are often a sign of past severe inflammation, but their role in increasing cancer risk is controversial. While some studies link them to higher risks, others do not find a direct connection. They are, however, a marker for the need for careful monitoring.
Age and Duration of Disease
The risk of colorectal cancer increases with the duration of IBD and is higher in patients diagnosed at a younger age. The earlier the onset of the disease, the longer the exposure to risk factors like inflammation, highlighting the need for early and regular screening.
Frequently Asked Questions
Yes, severe and chronic inflammation increases cancer risk.
They indicate past inflammation and may need monitoring.
Yes, younger onset means longer exposure to risk factors.
Regular screening and managing inflammation are key.
The Bottom Line
Identifying and managing risk factors is crucial in preventing cancer in IBD patients.
References
- Gupta RB, Harpaz N, Itzkowitz S, et al. Histologic inflammation is a risk factor for progression to colorectal neoplasia in ulcerative colitis: a cohort study. Gastroenterology 2007; 133:1099.
- Rutter MD, Saunders BP, Wilkinson KH, et al. Cancer surveillance in longstanding ulcerative colitis: endoscopic appearances help predict cancer risk. Gut 2004; 53:1813.
This article has been reviewed for accuracy by one of the licensed medical doctors working for Doctronic. Always discuss health information with your healthcare provider.
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