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Are You at Risk for Primary Hyperparathyroidism?
Published: Nov 08, 2023
Identifying risk factors for primary hyperparathyroidism can help you take action before symptoms develop.
Genetic Predispositions
Some people inherit a genetic risk for primary hyperparathyroidism. Conditions like Multiple Endocrine Neoplasia (MEN) and Familial Isolated Hyperparathyroidism are linked to genetic mutations that increase risk. If you have a family history of such conditions, genetic testing might be recommended.
Environmental and Lifestyle Factors
Exposure to radiation and certain chemicals can increase your risk of developing primary hyperparathyroidism. Lifestyle factors, such as low calcium intake, can also contribute by causing chronic stimulation of the parathyroid gland. Ensuring adequate calcium intake and minimizing radiation exposure can help mitigate these risks.
Medications and Other Medical Conditions
Certain medications, such as lithium, can affect calcium and parathyroid hormone levels, increasing the risk of hyperparathyroidism. Additionally, conditions like chronic kidney disease may contribute to altered calcium metabolism, enhancing susceptibility. Regular medical check-ups can help monitor and manage these risks.
Frequently Asked Questions
Genetic factors, radiation exposure, and certain medications can increase risk.
Yes, low calcium intake can increase risk by overstimulating the parathyroid gland.
Yes, genetic tests can identify mutations linked to the condition.
Some medications like lithium can increase the risk of hyperparathyroidism.
Wrapping Up
Understanding your risk factors for primary hyperparathyroidism can help you take proactive steps to manage your health.
References
- Minisola S, Arnold A, Belaya Z, et al. Epidemiology, Pathophysiology, and Genetics of Primary Hyperparathyroidism. J Bone Miner Res 2022; 37:2315.
- Pollak MR, Brown EM, Chou YH, et al. Mutations in the human Ca(2+)-sensing receptor gene cause familial hypocalciuric hypercalcemia and neonatal severe hyperparathyroidism. Cell 1993; 75:1297.
This article has been reviewed for accuracy by one of the licensed medical doctors working for Doctronic. Always discuss health information with your healthcare provider.
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