Are You at Risk for Melanoma? 5 Surprising Factors to Consider
Published: Dec 13, 2023
When it comes to melanoma risk, there's more to consider than just sun exposure. Some factors might surprise you.
Contents
The Mole Mystery
Having lots of moles isn't just a cosmetic issue - it's a risk factor for melanoma. If you have more than 50 moles, your risk is significantly higher. But it's not just about quantity; the type of moles matters too. Atypical or 'dysplastic' moles can be a red flag.
The Family Connection
Genetics play a big role in melanoma risk. If you have a close relative with melanoma, your risk is about doubled. Some families even have a condition called FAMMM syndrome, which dramatically increases melanoma risk.

The Immune System Link
People with weakened immune systems, such as organ transplant recipients or those with HIV, have a higher risk of melanoma. This is partly because the immune system helps detect and destroy abnormal cells, including potential cancer cells.
The Surprising Suspects
Some unexpected factors may influence melanoma risk. For instance, people with Parkinson's disease have a higher risk of melanoma. Certain medications, like some used to treat erectile dysfunction, have been linked to increased risk, though more research is needed.
Frequently Asked Questions
Yes, redheads have a higher risk due to genetic factors affecting skin pigmentation.
Some studies suggest a diet rich in antioxidants may help, but more research is needed.
Surprisingly, smoking hasn't been found to increase melanoma risk.
Knowledge is Power
Understanding these risk factors can help you take control of your skin health.
References
- Gandini S, et al. Meta-analysis of risk factors for cutaneous melanoma: III. Family history, actinic damage and phenotypic factors. Eur J Cancer 2005; 41:2040.
- Kubica AW, Brewer JD. Melanoma in immunosuppressed patients. Mayo Clin Proc 2012; 87:991.
- Dalvin LA, et al. Parkinson Disease and Melanoma: Confirming and Reexamining an Association. Mayo Clin Proc 2017; 92:1070.
This article has been reviewed for accuracy by one of the licensed medical doctors working for Doctronic. Always discuss health information with your healthcare provider.
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