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Are You at Risk for Diabetic Polyneuropathy?
Published: Mar 22, 2024
Identifying risk factors for diabetic polyneuropathy can help in early detection and prevention of this debilitating condition.
The Role of Hyperglycemia
Hyperglycemia, or high blood sugar, is a major risk factor for diabetic polyneuropathy. Prolonged high blood sugar levels can damage nerves by causing metabolic imbalances and oxidative stress. This nerve damage often begins in the extremities, leading to symptoms like numbness and pain.
Metabolic Syndrome and Its Impact
Metabolic syndrome, which includes conditions like obesity, high blood pressure, and abnormal cholesterol levels, increases the risk of diabetic neuropathy. This syndrome contributes to nerve damage by exacerbating oxidative stress and inflammation, further harming nerve fibers.
Duration and Control of Diabetes
The length of time a person has diabetes and how well they control their blood sugar are significant risk factors. Longer duration of diabetes increases the likelihood of nerve damage, while good blood sugar control can help prevent or delay the onset of polyneuropathy.
Frequently Asked Questions
High blood sugar levels and metabolic syndrome are key risk factors.
It increases oxidative stress and inflammation, damaging nerves.
Yes, maintaining blood sugar levels can lower the risk of neuropathy.
Key Takeaways
Understanding and managing risk factors can significantly reduce the chances of developing diabetic polyneuropathy.
References
- Feldman EL, Callaghan BC, Pop-Busui R, et al. Diabetic neuropathy. Nat Rev Dis Primers 2019; 5:41.
- Eid SA, Rumora AE, Beirowski B, et al. New perspectives in diabetic neuropathy. Neuron 2023; 111:2623.
- Zochodne DW. Sensory Neurodegeneration in Diabetes: Beyond Glucotoxicity. Int Rev Neurobiol 2016; 127:151.
This article has been reviewed for accuracy by one of the licensed medical doctors working for Doctronic. Always discuss health information with your healthcare provider.
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