Are You at Risk for C. difficile Infection?

Published: Apr 25, 2024

C. difficile infection (CDI) is a growing threat, especially for older adults and those recently on antibiotics. Understanding the risk factors can help prevent serious health issues.

Antibiotics: A Double-Edged Sword

While antibiotics fight off harmful bacteria, they also disrupt the good bacteria in your gut. This disruption can create an environment where C. difficile thrives, leading to infection. Certain antibiotics, like clindamycin and fluoroquinolones, are more likely to trigger CDI.

Age and Hospitalization: Added Risks

Individuals over 65 years old and those recently hospitalized are at higher risk for CDI. Hospitals can be breeding grounds for C. difficile due to the widespread use of antibiotics and the close quarters of patients, which facilitates bacterial spread.

Factors that increase the risk of C. difficile infection include recent antibiotic use, advanced age, and recent hospitalization. These conditions can disrupt gut flora, making individuals more susceptible to infection.

Other Contributing Factors

Using proton pump inhibitors (PPIs) can also increase the risk of CDI. PPIs reduce stomach acid, which can otherwise help control bacterial growth. An insufficient immune response to C. difficile toxins might also play a role in increasing susceptibility to infection.

Frequently Asked Questions

Antibiotic use and recent hospitalization increase CDI risk.

People over 65 and those hospitalized are most at risk.

Yes, PPIs can increase the risk of CDI.

Key Takeaways

Understanding these risk factors is crucial in preventing CDI.

Next steps: Talk to Doctronic about managing your risk for CDI.

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References

Bagdasarian N, et al. Diagnosis and treatment of Clostridium difficile in adults: a systematic review. JAMA 2015; 313:398.

Wanahita A, et al. Conditions associated with leukocytosis in a tertiary care hospital. Clin Infect Dis 2002; 34:1585.

Always discuss health information with your healthcare provider.