Are Injections a Game-Changer for Dupuytren's Contracture?
Published: May 04, 2024
Learn about the latest treatment options for Dupuytren's Contracture, including promising injections that might just bend the rules.
Contents
Understanding the Condition
Dupuytren's Contracture causes fingers to curl into the palm due to thickened tissues, leading to stiffness. While not life-threatening, it can significantly impact hand function and quality of life. The condition is more prevalent among older men of Northern European descent.
Glucocorticoid Injections
For those with early-stage Dupuytren's, glucocorticoid injections may provide relief from pain and slow progression. These injections target the painful nodules to reduce inflammation and discomfort. However, they are more effective in the initial stages and may not halt the condition's advancement.

Collagenase Injections
Collagenase injections offer a non-surgical option for treating contractures by breaking down the collagen in cords. This can improve finger flexibility significantly, although results can vary. It's considered a suitable alternative for patients preferring to avoid surgery.
Frequently Asked Questions
They reduce inflammation in nodules.
Yes, they help improve flexibility.
Injections manage but don't cure it.
Not always, injections may suffice.
Wrapping Up
Could these injections replace surgery for Dupuytren's Contracture?
References
- Hurst LC, Badalamente MA. Enzyme injection as nonsurgical treatment of Dupuytren's disease. J Hand Surg Am 2000; 25:629.
- Ketchum LD, Donahue TK. The injection of nodules of Dupuytren's disease with triamcinolone acetonide. J Hand Surg Am 2000; 25:1157.
This article has been reviewed for accuracy by one of the licensed medical doctors working for Doctronic. Always discuss health information with your healthcare provider.
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