Achalasia Relief: How Botulinum Toxin and Medications Can Help
Published: Jan 13, 2024
For those not ready for surgery, botulinum toxin and medications offer alternative ways to manage achalasia symptoms. Let's dive into these options.
Botulinum Toxin Injections
Botulinum toxin injections involve introducing a toxin into the LES to relax it by temporarily paralyzing the muscle. This can offer quick relief, but the effects are temporary, often requiring repeat treatments within months.
Pharmacologic Treatments
Medications like nitrates or calcium channel blockers can be used to reduce LES pressure, offering symptom relief. However, they are often less effective and can have side effects like headaches or dizziness.

Frequently Asked Questions
It relaxes the LES to improve swallowing.
They can help but are generally less effective than other treatments.
Effects are temporary, often lasting a few months.
Conclusion
Non-surgical options like botulinum toxin and medications offer temporary relief for achalasia symptoms.
References
- Boeckxstaens GE, et al. Achalasia. Lancet 2014; 383:83.
- Kahrilas PJ, et al. Clinical Practice Update: The Use of Per-Oral Endoscopic Myotomy in Achalasia: Expert Review and Best Practice Advice From the AGA Institute. Gastroenterology 2017; 153:1205.
This article has been reviewed for accuracy by one of the licensed medical doctors working for Doctronic. Always discuss health information with your healthcare provider.
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