7 Surprising Risk Factors for Invasive Strep A: Are You at Risk?
Published: Oct 14, 2023
Invasive Group A Streptococcus (GAS) infections can be life-threatening, and some risk factors might surprise you. Understanding these can help you stay vigilant and protect your health.
Contents
Unexpected Risk Factors
While age and immune status are known risks, other factors are less obvious. These include recent minor injuries like bruises or muscle strains, use of non-steroidal anti-inflammatory drugs (NSAIDs), and recent viral infections like flu or chickenpox. Even conditions like obesity and peripheral vascular disease can increase your risk.
The NSAID Connection
The link between NSAIDs and severe GAS infections is particularly concerning. These common pain relievers might mask early symptoms, delaying diagnosis. They may also affect your immune response, making infections more likely to become severe. If you've had a minor injury, consider alternatives to NSAIDs for pain relief.

Lifestyle and Environmental Risks
Certain lifestyles can increase your risk of invasive GAS. Intravenous drug use is a significant risk factor. Homelessness also increases risk, possibly due to limited access to healthcare and hygiene facilities. Recent surgeries or burns can also make you more vulnerable to these serious infections.
Medical Conditions That Increase Risk
Several health conditions can make you more susceptible to invasive GAS. These include diabetes, cancer, and heart disease. If you have these conditions, it's important to be extra vigilant about any signs of infection. Pregnancy and the postpartum period also carry increased risk for invasive GAS infections.
Frequently Asked Questions
Indirectly, as stress can weaken your immune system.
Young children and adults over 50 have the highest risk.
Good hygiene and prompt treatment of skin injuries help.
It's not typically spread person-to-person like strep throat.
It's rare, affecting about 3.5 per 100,000 people annually.
Knowledge is Power
Understanding your risk factors for invasive GAS can help you stay alert and seek prompt medical attention if needed.
References
- Factor SH, et al. Invasive group A streptococcal disease: risk factors for adults. Emerg Infect Dis 2003; 9:970.
- Stevens DL. Could nonsteroidal antiinflammatory drugs (NSAIDs) enhance the progression of bacterial infections to toxic shock syndrome? Clin Infect Dis 1995; 21:977.
- Laupland KB, et al. Invasive group A streptococcal disease in children and association with varicella-zoster virus infection. Ontario Group A Streptococcal Study Group. Pediatrics 2000; 105:E60.
This article has been reviewed for accuracy by one of the licensed medical doctors working for Doctronic. Always discuss health information with your healthcare provider.
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